AIM: This study aims to assess and monitor the prescribing pattern of antibiotics by using WHO prescribing indicators. OBJECTIVES: To assess the prescribing pattern of antibiotics, to know the common class of antibiotics and to assess the prescribing pattern using WHO prescribing indicators. METHODOLOGY: It is a prospective, observational study conducted at RIMS Hospital in the department of Paediatrics. Data collection was be done by using self-prepared patient Data collection form and WHO Prescribing Indicators. Microsoft excel was used for recording the data of recruited subjects. RESULTS: In our study the total percentage of male paediatric patients were comparatively more(58%) than that of female paediatric patients (42%). In the present study we observed that Cephalosporins group of antibiotics were most commonly prescribed. In our study we observed that average number of drugs per encounter was 5.2. Antibiotics were prescribed with 79.6% per encounter and most of drugs were prescribed from EDL of hospital. The excessive use of Parenterals is common in many developing countries. In this study 64.01%of antibiotics were given by Parenterals. CONCLUSION: On evaluation of study the use of antibiotics and injections were found to be high. Generic prescribing is more, and prescribing of drugs from EDL was found to be excellent.