Current research on drug development has emphasized on traditional uses of herbal constituents which were practiced in ancient times. Many parts of Feronia limonia were prescribed for diseases in ancient medicine of Asia. Recently, the active constituents of the fruit pulp have been studied extensively to support the traditional uses. The most important pharmacological actions of the fruit pulp are antioxidant and anticancer activities. These effect may be attributed to its high phenol contents. In-vivo and in-vitro studies of pharmacological effects of the fruit pulp have provided scientific knowledge on its potential use in many diseases such as liver failure, myocardial infarct, ischemic stroke, renal failure, diabetic mellitus and gastric ulcers. This review focuses on pharmacological and medicinal properties of Feronia limonia fruit pulp in prevention and treatment of various diseases. The information was gathered from articles which have been published in international journals and which are available online. The outcome of this review provides concise knowledge on pharmacological effects and possible mechanisms which are essential for developing therapeutic uses of the fruit pulp. It can be concluded that Feronia limonia fruit pulp has various pharmacological actions which can be utilized in treatment of many diseases if the active constituents for respective actions are identified in the future.