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ZENODO
Dataset . 2018
License: CC BY
Data sources: Datacite
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Dataset . 2018
License: CC BY
Data sources: Datacite
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Claim

Determining the nanoBRET AL2K IC50 values of 24 new ACVR1/ALK2 inhibitors

Research datakeyboard_double_arrow_right Dataset 19 Dec 2018Publisher:Zenodo
Authors: Wong, Jong Fu; , Alex;

doi: 10.5281/zenodo.2410328 , 10.5281/zenodo.2410327

Determining the nanoBRET AL2K IC50 values of 24 new ACVR1/ALK2 inhibitors

Abstract

In an effort to develop clinical compounds for Diffused Intrinsic Pontine Glioma (DIPG) treatment, new analogues of ACVR1/ALK2 inhibitors are continuously synthesised by Ontario Institute for Cancer Research (OICR) and Charles River Laboratories (CRL). I will provide prompt feedback of the cellular assay results to guide their design of new compounds. The blog post for this page can be found on the SGC opennotebook site: https://openlabnotebooks.org/determining-the-nanobret-al2k-ic50-values-of-24-new-acvr1-alk2-inhibitors/

Keywords

Inhibitor, NanoBRET, ACVR1, ALK2

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
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