This repository contains the supporting dataset, analysis code, supporting tables, and final figure files for the study entitled “Pressure behavior in a roller pump-driven low-flow VACC mock circuit with inactive de-airing pump: a descriptive bench characterization under reduced patient-side effective filling pressure conditions”. The repository includes the replicate-level dataset, a Google Colab-compatible Jupyter notebook, S1 and S2 Tables in DOCX format, and final TIFF figure files. The notebook reproduces the statistical analyses, S1 and S2 Tables, Figs 2–4, and S1 and S2 Figs from the replicate-level dataset.