GSE142512

Paul, Ruiz Pinto

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Dataset . 2026

License: CC BY

Data sources: Datacite

GSE142512

GSE142512 DNA methylation resources for Bioconductor ExperimentHub. Files are RangedSummarizedExperiment objects for GPL13534/450K and GPL21145/EPIC arrays, containing beta, M, and CN assays with sample metadata and hg19 genomic ranges.

Research datakeyboard_double_arrow_right Dataset 06 Jul 2026Publisher:Zenodo

Authors: Paul, Ruiz Pinto;

doi: 10.5281/zenodo.21198533

GSE142512

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Abstract

This dataset contains processed DNA methylation resources derived from GEO Series GSE142512 through a Bioconductor ExperimentHub package named GSE142512. The resources are stored as RangedSummarizedExperiment objects. The GPL13534/450K resource contains 485,512 CpG loci across 184 samples from 84 subjects. The GPL21145/EPIC resource contains 865,859 CpG loci across 211 samples from 90 subjects. Each object includes beta values, M values, copy number estimates, genomic ranges, sample-level phenotype metadata, and provenance metadata. The source study is Johnson et al., "Longitudinal DNA methylation differences precede type 1 diabetes", Scientific Reports, 2020, DOI: 10.1038/s41598-020-60758-0. The original public data are available from GEO accession GSE142512.

Related Organizations

Queensland University of Technology
Australia

Keywords

RangedSummarizedExperiment, DNA methylation, Infinium MethylationEPIC, type 1 diabetes, SummarizedExperiment, GPL21145, Bioconductor, GSE142512, ExperimentHub, Illumina HumanMethylation450, GPL13534

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