We present a rigorous algebraic derivation of two dimensionless constants associated with the quantum vacuum: $$R_{\text{fund}} = \frac{\ln 2}{6\ln 3} \approx 0.105155, \qquad \kappa_{\text{info}} = \frac{\ln 2}{4\ln 3} \approx 0.157732$$ These constants, termed the vacuum informational impedance and the information-expansion coupling, are analytically deduced without empirical fitting from the intersection of three established theoretical pillars of modern mathematical physics: Topological Gauge Symmetry: The true global gauge group of the Standard Model is the quotient $(SU(3)_C \times SU(2)_L \times U(1)_Y)/\mathbb{Z}_6$, which introduces a fractional topological granularity. Independently, the noncommutative geometry of the internal space imposes a strict KO-dimension 6 constraint, providing a rigid topological origin for the integer 6. Quantum Gravity and Fractal Geometry: In the spin-network formalism of loop quantum gravity, bulk volume nodes carry an entanglement entropy $S_{\text{volume}} = \ln 3$ (valence 3), while boundary punctures possess $S_{\text{boundary}} = \ln 2$ (spin-$1/2$). The fractional entropy reduction $\ln 2/\ln 3$ coincides exactly with the Hausdorff dimension of the middle-third Cantor set ($D_{\text{Cantor}}$). Horizon Thermodynamics: The dimensional projection efficiency ($\beta = 3/4$) is derived non-perturbatively from the $\text{AdS}_5/\text{CFT}_4$ correspondence strong-to-weak free energy ratio and black hole evaporation entropy bounds. When these topological, holographic, and thermodynamic factors are synthesised, their integer coefficients cancel exactly: $$\kappa_{\text{info}} = 2\beta R_{\text{fund}} = 2 \cdot \frac{3}{4} \cdot \frac{\ln 2}{6\ln 3} = \frac{\ln 2}{4\ln 3}$$ Both constants are proven to be strictly transcendental via the Gelfond–Schneider theorem, which guarantees the asymptotic stability of the vacuum against discrete phase transitions. 🧠 New in this Version: Physical Justifications & Ontological Implications Beyond the formal algebraic derivations, this major update introduces a comprehensive conceptual framework answering why nature selects these specific values. It provides physical justifications grounded in topological necessity, entropic parsimony (equipartition of the vacuum), and asymptotic stability. Most remarkably, it reveals an exact cross-domain mathematical identity: $R_{\text{fund}}$ is shown to coincide precisely with the maximal informational efficiency (Return on Investment) of the sieve of Eratosthenes at the critical primorial transition to modulus 6, establishing this structure as a universal information-theoretic fixed point. Furthermore, it explores the deep ontological implications of the theory by formulating three motivated conjectures: The topology of the holographic boundary as a fractal Cantor space. The emergence of self-similar perturbative scaling restricted to odd powers for gauge fields. The spectral action origin of the classical geometric $4\pi^3 + \pi^2 + \pi$ term. 🚀 Direct Physical Application: These derived invariants serve as the exact foundational inputs injected into our companion paper "Analytical Evaluation of the Electromagnetic Coupling Constant via Modular Substrate Vacuum Invariants" (Submitted to PTEP, Paper ID: T06182), enabling a parameter-free calculation of $\alpha^{-1}$ matching the CODATA 2022 recommended value to 14 decimal places. Status: Submitted to Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences (Manuscript ID: RSPA-2026-0598).