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Signaling granules formed by oncogenic NTRK2 fusion proteins sequester and activate proteins that regulate multiple cellular processes to drive oncogenic activity

Authors: Donoghue, Daniel; Whisenant, Thomas; Yang, Wei;

Signaling granules formed by oncogenic NTRK2 fusion proteins sequester and activate proteins that regulate multiple cellular processes to drive oncogenic activity

Abstract

Supplemental Tables for Research Article under consideration for publication, submitted June 17, 2026 to journal "Cell Cycle." Article is entitled: "Signaling granules formed by oncogenic NTRK2 fusion proteins sequester and activate proteins that regulate multiple cellular processes to drive oncogenic activity." Authors: Wei Yang, Thomas C. Whisenant, Daniel J. Donoghue. Institution: University of California, San Diego Supplemental Table S1: 190 Proteins Identified with p-value < 0.05, Sorted by p-value. Supplemental Table S2: Total Proteomic Results Identified 4917 Proteins from All Replicates. KD = Kinase Dead NACC2-NTRK2. WT= Wild Type NACC2-NTRK2. Supplemental Table S3: Total Peptides Identified from All Replicates. KD = Kinase Dead NACC2-NTRK2. WT= Wild Type NACC2-NTRK2. Supplemental Table S4: Total Phosphopeptides Identified. Total of 16398 Peptides. KD = Kinase Dead NACC2-NTRK2. WT = Wild Type NACC2-NTRK2

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