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imgag/ngs-bits: 2026_06

Authors: Marc Sturm; Alexandr Chernov; Leon Schütz; Alexander Ott; Axel Gschwind; c-schroeder; Florian Lenz; +11 Authors

imgag/ngs-bits: 2026_06

Abstract

Changes: removed Qt5 support added tools: NGSDExportSpliceAI, NGSDImportCSpec, NGSDTransferReportConfig, SampleIdentity, TranscriptToProtein, TsvAnnotate, TsvTo, VcfAnnotateFrequency, VcfMerge BedAnnotateFreq: changed default for -min_mapq from 1 to 20 BedIntersect: added parameter -annotation NGSDExportGenes: added gnomAD pli column NGSDExportAnnotationData: Gene info entries now contains only keys with a value TrioMendelianErrors: added parameter -dot_as_wt UpdHunter: added parameter -var_use_special_calls and fixed bug in handling of exclude regions. VcfAnnotateFromBed: added parameter -desc VcfFilter: added parameters -info_flags and -info_flags_exclude NGSD changes: added table user_action_permissions for action permissions of restricteed users in GSvar added table analysis_time for tracking analysis times of megSAP analyses added table report_configuration_failed_transfer for manually fixing report configs that could not be transferred from one sample to another automaticalls added table db_import_info to track version/date of database imports into NGSD added table cspec_data for gene-specific guidelines for variant interpretation table geneinfo_germline: added field gnomad_pli table somatic_cnv_callset: made field ps_normal_id nullable to allow import of tumor-only variants table somatic_snv_callset: made field processed_sample_id_normal nullable to allow import of tumor-only variants table repeat_expansion: added field min_pathogenic_hom to allow lower cutoff if the repeat expansion is homozygous Full Changelog at: https://github.com/imgag/ngs-bits/compare/2025_12...2026_06 Note: Please do not use the auto-generated 'Source code' packages - they will not work!

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