Synthetic data generation has emerged as a promising solution to overcome the challenges which are posed by data scarcity and privacy concerns, as well as, to address the need for training artificial intelligence (AI) algorithms on unbiased data with sufficient sample size and statistical power. Our review explores the application and efficacy of synthetic data methods in healthcare considering the diversity of medical data. To this end, we systematically searched the PubMed and Scopus databases with a great focus on tabular, imaging, radiomics, time-series, and omics data. Studies involving mResearch goal: How do tabular generative evaluation metrics scale in performance when applied to multimodal models with varying degrees of adversarial noise in the training data?Autonomous synthesis report generated by SOVEREIGN Research Kernel. Tribunal consensus score: 8.3/10.