The rapid advancement of generative artificial intelligence (AI) is reshaping educational practices, particularly withinblended learning environments that combine face-to-face and online instruction. Among emerging AI technologies, ChatGPT hasgained significant attention for its ability to provide personalized learning support, instant feedback, content generation, and interactiveacademic assistance. This paper examines the integration of ChatGPT into blended learning environments and explores its potential asa transformative tool for AI-driven education. Drawing upon recent scholarly literature, the study investigates the role of ChatGPT inenhancing teaching and learning processes, fostering student engagement, supporting self-directed learning, and improvinginstructional efficiency. The paper further analyzes the diverse educational applications of ChatGPT, including adaptive tutoring,assessment support, collaborative learning facilitation, and academic research assistance. While the findings indicate that ChatGPToffers substantial opportunities for personalization, accessibility, learner autonomy, and inclusive education, several challenges remain.Concerns related to AI hallucinations, academic integrity, ethical and privacy issues, digital inequity, teacher readiness, and excessivedependence on AI highlight the need for responsible implementation. To address these concerns, the study proposes a framework foreffective integration based on a Human–AI Partnership Model, pedagogically guided use, faculty capacity building, ethical AIgovernance, and institutional support systems. The paper concludes that ChatGPT has the potential to significantly enhance blendedlearning when deployed within a robust pedagogical and ethical framework, positioning AI as a powerful complement to humanexpertise rather than a substitute for educators