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QuPath Atölye Eklentisi (QuPath Workshop Extension): Patologlar için tek-tıkla İHK kantifikasyon ve dijital patoloji eğitim araç seti

Authors: Balcı, Serdar;

QuPath Atölye Eklentisi (QuPath Workshop Extension): Patologlar için tek-tıkla İHK kantifikasyon ve dijital patoloji eğitim araç seti

Abstract

A QuPath 0.6+ extension that bundles the Patologlar için QuPath Atölyesi (QuPath Workshop for Pathologists) Groovy scripts as one-click menu entries under Extensions → Atölye. Workflow modules: cell detection (M2), nuclear IHC scoring (M3 — Ki-67; M3b — ER/PR H-score), membrane IHC scoring (M4 — HER2, with Cellpose primary detector and WatershedCellMembraneDetection automatic fallback), cytoplasmic IHC scoring (M5 — CD68), tumor-vs-stroma classification (M6), tumor-restricted scoring (M7), and measurement export (M9). Utility helpers: orphan detection cleanup, image-type setup (per-slide or project-wide), and threshold re-binning of existing detections without re-running cell detection. The bundled HER2 pipeline implements both a cell-based H-score and a parallel pixel-wise H-score adapted from Sara McArdle's published Groovy script (method: Ram et al., PLoS One 2021). Scope: research and education only — produces numerical measurements (counts, percentages, intensities, H-scores, densities); clinical interpretation is explicitly out of scope. Companion workshop site: atolye.patoloji.dev

Cite all versions using DOI 10.5281/zenodo.20375397 — this DOI represents all versions and always resolves to the latest one. Companion workshop website at https://atolye.patoloji.dev. The extension JAR is also distributed via OSF at https://osf.io/v7mjq alongside the workshop slide set and pixel classifier.

Keywords

WSI, H-score, pathology education, Turkish, IHC quantification, Groovy, QuPath, HER2, immunohistochemistry, tumor-stroma segmentation, whole slide image, Ki-67, ER/PR, Cellpose, digital pathology, computational pathology

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average