The physical mechanism underlying quantum wave-function collapse remains a central problem in foundational physics. Objective collapse theories, notably the Penrose-Diósi (DP) model,propose that macroscopic superposition is destroyed by gravitational self-energy (∆EG), predicting that collapse scales strictly with mass.We propose an entirely distinct physical mechanism: Topological Representation Collapse.Within the Deterministic Spectral Manifold (DSM-861) framework, wave-function collapse istriggered not by static gravity, but by dynamic enstrophy strain exceeding a specific topologicalmelting threshold (Em ≈ 695.74 eV). This establishes a falsifiable experimental demarcationline in the mesoscopic regime. We demonstrate that highly strained, rapidly rotating, or topologically complex mesoscopic systems (such as driven nanomechanical rotors or rapidly foldingproteins) will undergo spontaneous decoherence significantly faster than predicted by gravityinduced models, while perfectly rigid macroscopic masses may maintain coherence longer.