Persistent gaps between the acquisition of knowledge and its consistent application in clinical practice continue to be a concern in radiologic education and patient care settings. Therefore, this study examined the relationship between knowledge and clinical practice of radiologic technology interns regarding the Radiologic Technology Code of Ethics during clinical internship. Specifically, it assessed interns’ knowledge in terms of responsibility to patients, evaluated their ethical clinical practice, determined the relationship between the two variables, and proposed an action plan based on the findings. A descriptive-correlational design was employed involving sixty-seven (67) radiologic technology interns in Calamba City during the academic year 2025–2026, selected through total population sampling. Data were collected using a structured questionnaire and analyzed using weighted mean and Spearman rho. Results showed that interns demonstrated high knowledge (M = 0.62), particularly in providing care aligned with professional standards and informed consent. Their clinical practice was rated satisfactory (M = 3.17), with strong adherence observed in the application of the As Low as Reasonably Achievable (ALARA) principle and patient communication. Further analysis revealed a significant moderate positive relationship between knowledge and clinical practice (r = 0.54, p = 0.04), suggesting that better understanding of ethical principles is associated with improved clinical behavior. Despite this, gaps remain in understanding professional boundaries and consistently applying value-based ethical decision-making. In response, an action plan was proposed to strengthen awareness of professional scope, reinforce ethical judgment, and improve the application of knowledge through structured case analysis, reflective writing, and mini skill reminder tools to support more consistent and ethical clinical practice.