Chronic Obstructive Pulmonary Disease (Copd) Represents A Major Global Health Burden, Ranking As The Third Leading Cause Of Death Worldwide (1). While Primarily Characterized By Progressive Airflow Limitation, Copd Is Increasingly Recognized As A Systemic Disease With Significant Extrapulmonary Manifestations. Among These, Renal Dysfunction Has Emerged As A Clinically Important But Frequently Underdiagnosed Complication (2). Epidemiological Data Indicate That Renal Impairment Affects 25–50% Of Copd Patients, Yet It Often Remains Undetected Until Advanced Stages Due To The Absence Of Standardized Early Diagnostic Protocols (3). Chronic Systemic Inflammation, Hypoxemia, And Hemodynamic Alterations Associated With Copd Are Considered Key Pathogenetic Mechanisms Driving Renal Injury (4). Early Identification Of Renal Dysfunction In Copd Patients Is Therefore Critical For Preventing Disease Progression And Improving Long-Term Outcomes.