Background and Aim: Chronic diseases require long-term drug use in terms of reducing morbidity and mortality. Adherence with medication treatment; It is the name given to all the decisions about prescribing the patient's drugs, starting, continuing and discontinuing the drugs, and applying the recommendations received in this process. The aim of this study is to assessment the medication adherence levels of individuals with chronic diseases. Methods: The population of the study consisted of patients receiving treatment at Al-Nasiriyah Teaching Hospital in Dhi-Qar City, Iraq. Data were collected between December 2021 and May 2022. 208 patients were included in the study. Data were collected by face-to-face method using a socio-demographic questionnaire and General Medication Adherence Scale (GMAS). Results: The cost sub-dimension scores of those under the age of 45 were lower, those who were married, those who were illiterate, those who were literate, and those who did not have a job had lower co-morbidity and drug burden, cost sub-dimension, and total GMAS scores compared to those who were unemployed (p<0.05). Conclusion: Education programs should be organized and awareness should be raised about drug use regularly by nurses for patients who use drugs regularly, before and after they start using the drug.