Plants have been used for several thousands of traditional medical purposes to date and aregenerally based on the uses of local and natural products related to the indigenous people’sperception and way of life. Rainfall across Namibia varies considerably, increasing from 0 mm inthe southwest in the Namib desert to 600 mm to the northeast in the Caprivi strip. The data formedicinal plants used for studying medicinal purposes in Namibia and Angola was obtained usinga comprehensive review of medicinal plant species in Namibia and Angola and published worksie online databases such as Pub Med Central, Web of Science, Science Direct and Google Scholar.The authors have collected data on the medicinal properties of the plants and the typicalailments/diseases related to their applications. The diseases commonly encountered n daily life aretreated with medicinal plants are Headaches, flu, stomach pains, malaria, epilepsy, andwounds/burns. The common parts of the plants are the roots, bark leaves, fruits, and pods. Inaddition, the common ways of application are steaming, topical application, and ingestion. Themain objective of this study highlights in Namibia and Angola to identify the potential oftraditional drugs to cure which is very vital to evaluate the research findings which are of utmostimportance for the development of healthy and educated communities. The medicinal plant speciesdocumented are used to treat a variety of ailments, and several diseases.