This report synthesises findings from 12 peer-reviewed papers addressing the following research question: How does the performance of the proposed 3D CNN with fully connected CRF for brain lesion segmentation compare to transformer-based architectures on the BRATS benchmark in terms of accuracy and. 10 claims were extracted from source literature; 10 were independently verified against retrieved documents. An automated multi-reviewer quality assessment produced a score of 8.5/10. This report is a machine-generated literature synthesis and does not constitute original research.Research goal: How does the performance of the proposed 3D CNN with fully connected CRF for brain lesion segmentation compare to transformer-based architectures on the BRATS benchmark in terms of accuracy and inference efficiency?Autonomous literature synthesis. Automated review score: 8.5/10. Full text and citation available at Assignee Research.