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What estimation should be used for dose adjustments of antidiabetics, antimicrobials including antibiotics, NSAIDs, statins, and neuromodulators in renal insufficiency? With ClCr or with GFR?

descriptionPublicationkeyboard_double_arrow_right Other ORP type Under curationPublisher:Zenodo
Authors: Tripdatabase;

doi: 10.5281/zenodo.20533743

What estimation should be used for dose adjustments of antidiabetics, antimicrobials including antibiotics, NSAIDs, statins, and neuromodulators in renal insufficiency? With ClCr or with GFR?

Abstract

eGFR is generally preferred for dose adjustments in renal insufficiency, but CrCl remains important for drugs with narrow therapeutic indices or considerable renal excretion.

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