Plant stem cells have emerged as a promising area in cosmetic science due to their regenerative potential, antioxidant activity, and sustainable production methods. The growing demand for natural and eco-friendly cosmetic ingredients has accelerated research into plant-derived bioactive compounds and their applications in anti-aging and skin protection products. This review discusses the fundamentals of plant stem cells, extraction techniques, bioactive compounds, mechanisms of action, cosmetic applications, commercial trends, safety concerns, regulatory issues, and future innovations in the field.