This article examines the psychological aspects of the relationship between anxiety, personal characteristics, and the development of somatic diseases. The study analyzes the influence of individual psychological traits and anxiety levels on the manifestation and progression of somatic symptoms. The theoretical framework of the research is based on the biopsychosocial model, psychosomatic medicine, and stress-coping theory. The empirical study involved 120 patients diagnosed with somatic disorders and receiving treatment in therapeutic medical institutions in Tashkent.