Abstract The rapid escalation of global temperatures and shifting humidity patterns significantly alter the fundamental kinetics and pathways of chemical reactions within the Earth’s atmosphere. This review examines the emerging trends in tropospheric chemistry as influenced by climate change, with a specific focus on the transformation of Volatile Organic Compounds (VOCs). Through a systematic analysis of recent literature (2020–2026), this study evaluates how thermal energy increases accelerate oxidation rates and modify the lifecycle of biogenic and anthropogenic organic emissions. Key findings highlight the critical shifts in Secondary Organic Aerosol (SOA) formation, where temperature-induced changes in gas-particle partitioning affect air quality and radiative forcing. Furthermore, the paper discusses the feedback loops between rising methane concentrations and the availability of hydroxyl radicals (OH), which serve as the primary atmospheric "detergent." By synthesizing data on photochemical reaction rates and ozone cycle disruptions, this research identifies significant gaps in current climate-chemical models. This review aligns with the conference theme "Innovation Beyond Boundaries" by bridging environmental science with advanced organic reaction mechanisms, providing a roadmap for future interdisciplinary atmospheric research. These insights are vital for developing robust mitigation strategies to address the complex chemical consequences of a warming planet.