Metabolism-related fatty liver disease (MAFLD) is a highly prevalent condition strongly associated with insulin resistance and metabolic syndrome. Liver fibrosis is the most important prognostic factor determining disease progression and long-term outcomes. The triglyceride–glucose (TyG) index is a simple and cost-effective surrogate marker of insulin resistance. Recent evidence suggests that the TyG index may be associated with liver fibrosis severity in MAFLD patients. This study aimed to evaluate the relationship between TyG index and liver fibrosis stages in adults with MAFLD using biochemical markers and noninvasive elastography.