This report synthesises findings from 14 peer-reviewed papers addressing the following research question: To what extent does layer aggregation depth reduce inference accuracy in graph neural networks evaluated on large-scale graph benchmark suites. Molecular machine learning has been maturing rapidly over the last few years. Improved methods and the presence of larger datasets have enabled machine learning algorithms to make increasingly accurate predictions about molecular properties. 10 claims were extracted from source literature; 9 were independently verified against retrieved documents. An automated multi-reviewer quality assessment produced a score of 8.5/10. This report is a machine-generated literature synthesis and does not constitute original research.Research goal: To what extent does layer aggregation depth reduce inference accuracy in graph neural networks evaluated on large-scale graph benchmark suites?Autonomous literature synthesis. Automated review score: 8.5/10. Full text and citation available at Assignee Research.