The building sector significantly contributes toenergy consumption, particularly in hot and humid regionswhere cooling and dehumidification demands are high. Inrapidly growing cities like Mumbai, Pune, and Nagpur, hightemperatures (30°C–38°C) and humidity levels (70–85%)increase reliance on mechanical cooling, leading to higherenergy use. This study presents a structured workflow forclimate-responsive building design to achieve Net ZeroEnergy Building (NZEB) performance. A seven-phasemethodology is adopted, including climate analysis usingTypical Meteorological Year (TMY) data, baseline modeldevelopment, and Building Energy Modelling (BEM) usingEnergyPlus and DesignBuilder. Passive and active strategiesare integrated to optimize performance, followed by solarphotovoltaic system implementation. Results show significantenergy reduction, enabling NZEB achievement and supportinga climate-specific framework aligned with ECBC guidelines.