ABSTRACT: Pain management is an essential component of nursing care, and the proper use of analgesic patches requires adequate knowledge and practical skills among nursing students. The present study aimed to assess the effectiveness of demonstration on analgesic patch regarding knowledge and practice among B.Sc. Nursing 2nd year students at a selected College of Nursing, Jabalpur (M.P.). A pre-experimental one group pre-test and post-test design was adopted among 60 nursing students. Data were collected using structured knowledge questionnaires and practice checklists before and after the demonstration programme. The findings revealed that before the intervention, 78.33% of students had poor knowledge regarding analgesic patches, whereas after the demonstration, 68.3% achieved average knowledge and 30% attained good knowledge. The mean post-test knowledge score (23.6) was significantly higher than the pre-test score (11.95), indicating the effectiveness of the demonstration method. The study concluded that demonstration significantly improved the knowledge and practice of nursing students regarding analgesic patch application and pain management.