BCR + GEX Tutorial Dataset: Single-cell BCR and gene expression data from tumor-draining lymph node and primary tumor of an ovarian cancer patient
BCR + GEX Tutorial Dataset: Single-cell BCR and gene expression data from tumor-draining lymph node and primary tumor of an ovarian cancer patient
Analysis-ready single-cell input data from one ovarian cancer patient, used in the BCR + GEX Integration Tutorial. The dataset includes paired lymph node (P1_LN) and primary tumor (P1_PT) samples from the same patient, originally published in Nathan et al. (2026, Immunity). Files include Cell Ranger GEX output (.h5 count matrices) and Cell Ranger VDJ output (filtered_contig.fasta, filtered_contig_annotations.csv, and airr_rearrangement.tsv for each sample). These files serve as starting inputs for the three-part tutorial hosted at https://github.com/Part-coder-part-batman. Pipeline outputs (processed BCR tables and annotated Seurat objects) are available in a separate Zenodo deposit at https://zenodo.org/records/20324083. Raw sequencing data are available on GEO under accession GSE319733.