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BCR + GEX Tutorial Dataset: Single-cell BCR and gene expression data from tumor-draining lymph node and primary tumor of an ovarian cancer patient

Authors: Nathan, Nachi;

BCR + GEX Tutorial Dataset: Single-cell BCR and gene expression data from tumor-draining lymph node and primary tumor of an ovarian cancer patient

Abstract

Analysis-ready single-cell BCR and gene expression data from one ovarian cancer patient, used in the BCR + GEX Integration Tutorial. The dataset includes paired lymph node (P1_LN) and primary tumor (P1_PT) samples from the same patient, originally published in Nathan et al. (2026, Immunity). Files include Cell Ranger GEX output (.h5), BCR sequence data (AIRR-format TSV), processed BCR data (bcr_data.tsv), and an annotated integrated Seurat object (RDS). These files serve as input and checkpoint files for the three-part tutorial hosted here. Raw sequencing data are available on GEO under accession GSE319733.

Keywords

Lymph/immunology, B cells, single-cell RNA-seq, Immcantation, Lymph Nodes/immunology, BCR, Single-Cell Gene Expression Analysis, ovarian cancer, Immune system, Memory B Cells, Seurat, Immune System, GEX, HGSOC, Lymph Nodes, BCR repertoire, Single-Cell Analysis, Immune System/immunology, Single-cell RNA-seq

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Related to Research communities
Cancer Research