The Horizon project NEMO (Next Generation Meta OS) builds an IoT-Edge-Cloud continuum in the form of an open-source, flexible meta-Operating System. However, this distributed continuum introduces significant cybersecurity and trust challenges that must be addressed end-to-end. CyberNEMO's primary objective is to build on top of NEMO to add end-to-end cybersecurity and trust across the IoT-Edge-Cloud-Data Computing Continuum. The project aims to establish a paradigm shift to support resilience, risk preparedness, awareness, detection, and mitigation within Critical Infrastructure deployments and across supply chains.