Technological advancements create opportunities for sophisticated cybercrimes that, through innovative tactics and techniques, pose serious security and financial risks to the EU and beyond. Combating cross-border cybercriminal activities requires a well-rounded response that goes beyond pure technology. ENSEMBLE's primary objective is to provide exactly such a response, at the nexus of advanced AI-based technological solutions, multi-stakeholder investigation processes, training, and awareness. The project focuses on detecting and preventing ransomware, cyber fraud, data theft and extortion, unauthorised access, and crypto-jacking.