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Short-Term Outcomes after Coronary Artery Bypass Grafting in Africa: A Narrative Systematic Review with New Evidence from Cameroon

Authors: Charles Mve Mvondo et al.;

Short-Term Outcomes after Coronary Artery Bypass Grafting in Africa: A Narrative Systematic Review with New Evidence from Cameroon

Abstract

The question this study addressed. This systematic review synthesised published CABG outcomes from Africa and added unpublished data from a Cameroonian cohort to identify predictors of early mortality. What this study adds to our knowledge. Pooled early mortality across African CABG series is 3.5%, but reaches 11.2% in some South African reports. In Cameroon, operative mortality was 4.5%. Key independent predictors of death were advanced heart failure (NYHA >III, OR=36.0), prolonged bypass time (≥180 min, OR=2.5) and major blood loss (≥2000 mL, OR=4.0). Across Africa, reduced ejection fraction and high EuroSCORE II also predict poor outcomes. This publication is available in full in Health Research in Africa.

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