X-ray diffraction images for yeast 5-aminolevulinic acid dehydratase co-crystallised with the substrate 5-aminolevulinic acid. The structure demonstrated a putative product-like intermediate bound covalently to Lys 263 with an amino side chain ligated to the active-site zinc ion in a position normally occupied by a catalytic hydroxide ion. The data were collected in two passes using the ESRF beamline ID29 in Feb 2002 and extend to approximately 1.6 Å resolution.

{"references": ["'X-ray structure of a putative reaction intermediate of 5-aminolaevulinic acid dehydratase.' Erskine, P. T., Coates, L., Butler, D., Youell, J. H., Brindley, A. A., Wood, S. P., Warren, M. J., Shoolingin-Jordan, P. M., Cooper, J. B. (2003). Biochem. J. 373, 733-738."]}