The study was done to critically examine institutional, structural, and policy dynamics that constrain Zimbabwe’s effective domestic resource mobilization. It aims to assess ways to overcome these constraints through some targeted reforms, institutional strengthening and strategic policy realignment. A mixed-methods research design was enacted by the researcher to critically examine the structural, institutional, and policy factors that is constraining effective domestic resource mobilization in Zimbabwe, as well as identifying viable avenues to reform. The study follows a sequential exploratory strategy (SES) which started by a qualitative method giving basis for quantitative method. The study revealed that continual fragmented policy environments, institutional inefficiencies, weak accountability mechanisms due to corruption, institutional politicalisation as well as macroeconomic instability significantly reduces DRM efforts. The study concluded that sustainable DRM strategy in Zimbabwe cannot be effectively addressed in isolation from institutional reforms and a broader governance. Without restoring effective fiscal discipline, enhancing institutional coordination and reconfiguring the policy framework to foster transparency and trust. The study recommended that there is need for institutional autonomy and capacity building strengthening, tax policies and fiscal policies needs to be aligned, there is need for building of trust in the local fiscal institutions and integration of domestic efforts with other global best practices.