This interactive guide takes practitioners through the steps of the REXUS Framework to help them select suitable solutions to address their WEFE Nexus challenges. Thereis a particular focus on ensuring that Nature-based Solutions (NbS) are considered alongside other solutions. This guide highlights a range of materials for selecting solutions that can address WEFE Nexus challenges and enhance resilience to the impacts of climate change. It considers the information that will likely be needed and how the various solutions could be assessed in a given context. Examples of solutions that could be included in an overarching WEFE Nexus strategy are also provided,both from the wider REXUS project and the associated pilot areas. The guide also discusses starting points for the next steps (implementation and monitoring) once solutions are identified. The guide is aimed primarily at practitioners. The guide is designed to help all those involved in the planning, assessment and stakeholder consultation stages of choosing solutions to include in a strategy to address WEFE Nexus challenges