Quality control and food safety standards are critical components of the global food industry, ensuring that food products are safe, nutritious, and fit for consumption. With increasing globalization, complex supply chains, and heightened consumer awareness, the need for robust quality management systems has intensified. This chapter provides a comprehensive overview of quality control principles, food safety frameworks, international standards, analytical methods, and regulatory requirements. Key systems such as Hazard Analysis and Critical Control Points (HACCP), ISO 22000, and Codex Alimentarius guidelines are discussed in detail. Emerging trends including digital traceability, artificial intelligence, and sustainability considerations are also explored. The chapter concludes by highlighting future challenges and the importance of integrated approaches in maintaining food safety and quality.