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All metadata and supplementary tables for NYGC ALS Consortium

Authors: Humphrey, Jack; Ali, Oku; Tokolyi, Alex; Bond, Marielle;

All metadata and supplementary tables for NYGC ALS Consortium

Abstract

All metadata and supplementary tables for the NYGC ALS Consortium flagship resource paper. NYGC_Flagship_ST_1_3_Metadata.xlsx Data dictionary - including column definitions Member list - all NYGC ALS Consortium member sites ST1: all WGS and donor-level clinical metadata ST2: WGS mutation annotations ALS gene list - all ALS genes used for annotations ST3: all RNA-seq metadata NYGC_Flagship_ST_4_16_expression.xlsx ST4: all case-control DEGs across tissues ST5: all GSEA GO analysis merged, with column for comparison and tissue ST6: all GO enrichment for tissue intersections ST7: all deconvolution estimates across all tissues and cell-types ST8: all deconvolution statistics, across all tissues and cell-types ST9: cell-type marker GSEA results ST11-15: clinical DEGs ST16: clinical GO/KEGG enrichment on age death and duration NYGC_Flagship_ST_17_31_splicing.xlsx ST17-22: Categorical Case-control, C9, limb-bulbar DS results at FDR < 0.05, long format, clusters and intron ST23-28: Continuous DS results, onset, death, duration (clusters and introns) ST29-31: DS enrichments NYGC_Flagship_ST_32_35_genetics.xlsx ST32: QTL discovery ST33: QTL sharing ST34: COLOC results ST35: STR-QTL results

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