The Book of Doers and 2025/26 Conference brought together a diverse group of experts, such as patient advocates, researchers, industry and non-profit colleagues, and community leaders, some with lived experience as well as professional expertise. These stakeholders from over 30 organisations shared their work through 19 case study contributions in The Book of Doers, presented these and related work at the conference and participated in panel sessions for open Q&A discussions, all of which collectively informed this commentary.