Present paper is an attempt study in a case study of Dr. Bandorwala Leprosy Hospital Kondhwa (Pune) the gender-wise temporal assessment of leprosy disease was investigated. Leprosy, often known as Hansen's disease, is caused by Mycobacterium leprosy. It is an infectious sickness that persists. It mostly affects the skin and peripheral nerves and can cause severe deformity and impairment if therapy is not received. Leprosy has been severely stigmatized throughout history and culture since it was first identified in antiquity. Leprosy is a bacterial disease that can be debilitating and persistent, and it is caused by Mycobacterium leprosy e. Cases of the illness have been reported in many countries, including India. Disease incidence is highest in the poorest part of the world. Migration from endemic to no endemic leprosy areas may cause the disease to resurface. To ascertain the quantity of leprosy cases in Pune. Every year, leprosy cases that occurred in Pune City between 2010 and 2021 were compiled and analyzed, allowing researchers to observe how the disease's cases changed over time.