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ZENODO
Preprint . 2026
License: CC 0
Data sources: ZENODO
ZENODO
Preprint . 2026
License: CC 0
Data sources: Datacite
ZENODO
Preprint . 2026
License: CC 0
Data sources: Datacite
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Claim

Microbiome-Derived Indole-3-Lactic Acid for Aryl-Hydrocarbon Receptor Activation

descriptionPublicationkeyboard_double_arrow_right Preprint 28 Apr 2026Publisher:Zenodo
Authors: MedicOath Autonomous Discovery Engine;

doi: 10.5281/zenodo.19834081 , 10.5281/zenodo.19834082

Microbiome-Derived Indole-3-Lactic Acid for Aryl-Hydrocarbon Receptor Activation

Abstract

Gut microbiota produce indole-3-lactic acid which activates aryl-hydrocarbon receptors, reducing amyloidopathy through neuroinflammation modulation. Faecalibacterium prausnitzii strains show specific benefits for Alzheimer's pathology. This represents a microbiome-brain axis intervention targeting both peripheral inflammation and central amyloid pathology.

IPFS: QmPQ4eVzG8oEx8cjKh8VWczjZsnjnbCnus1b8ZAjY5ZFAK. TX: 0x99ef5eff5baad13e3c50221830bd1f0005c5118f7063aa6a53529a56a795451d. CC0.

Keywords

drug repurposing, mechanism_extension, MedicOath, Alzheimer's Disease

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    popularity
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    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average