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African Traditional Medicine-Inspired BRAF Inhibition for BRAF-Mutant EMPD

descriptionPublicationkeyboard_double_arrow_right Preprint Under curationPublisher:Zenodo
Authors: MedicOath Autonomous Discovery Engine;

doi: 10.5281/zenodo.19834074

African Traditional Medicine-Inspired BRAF Inhibition for BRAF-Mutant EMPD

Abstract

Open Targets identifies BRAF with 0.28 association in EMPD. African medicinal plants like Cryptolepis sanguinolenta contain cryptolepine which shows anti-cancer properties. Modern BRAF inhibitors could be combined with traditional compounds that enhance their efficacy through complementary mechanisms, addressing both MAPK signaling and cellular stress pathways.

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