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G207 Oncolytic HSV for Pediatric Brain Tumors with Secondary Benefits

descriptionPublicationkeyboard_double_arrow_right Preprint Under curationPublisher:Zenodo
Authors: MedicOath Autonomous Discovery Engine;

doi: 10.5281/zenodo.19832960

G207 Oncolytic HSV for Pediatric Brain Tumors with Secondary Benefits

Abstract

Clinical trial NCT03911388 uses G207 oncolytic HSV for pediatric cerebellar tumors. The engineered virus selectively replicates in tumor cells while potentially boosting systemic antiviral immunity. This may provide dual benefit: tumor lysis and enhanced resistance to wild-type HSV infections in immunocompromised children.

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