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ZENODO
Preprint . 2026
License: CC 0
Data sources: ZENODO
ZENODO
Preprint . 2026
License: CC 0
Data sources: Datacite
ZENODO
Preprint . 2026
License: CC 0
Data sources: Datacite
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Claim

Topical Imiquimod-Calcipotriol Combination for Superficial Vulvar Extramammary Paget Disease

descriptionPublicationkeyboard_double_arrow_right Preprint 28 Apr 2026Publisher:Zenodo
Authors: MedicOath Autonomous Discovery Engine;

doi: 10.5281/zenodo.19832618 , 10.5281/zenodo.19832617

Topical Imiquimod-Calcipotriol Combination for Superficial Vulvar Extramammary Paget Disease

Abstract

ClinicalTrials.gov shows completed Phase 3 trial NCT02385188 tested topical 5% imiquimod for vulvar Paget's. Lens.org patents report successful 'Topical Calcipotriol Plus Imiquimod Immunotherapy' (2023). Imiquimod activates TLR7/8 inducing local immune response while calcipotriol modulates vitamin D receptor affecting cell differentiation.

IPFS: QmUFg94Zr6sNHjJJpsthUb16HRXAso9exCBST31JLv2624. TX: 0x0c0b2c8ace9311855ed920e5b2a048824ca4e7828c826a71daa4a0bf66ac96ee. CC0.

Keywords

combination, drug repurposing, MedicOath, Extramammary Paget disease

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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Powered by OpenAIRE graph
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average