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ZENODO
Other ORP type . 2026
License: CC BY
Data sources: ZENODO
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Other ORP type . 2026
License: CC BY
Data sources: ZENODO
ZENODO
Other ORP type . 2026
License: CC BY
Data sources: Datacite
ZENODO
Other ORP type . 2026
License: CC BY
Data sources: Datacite
ZENODO
Other ORP type . 2026
License: CC BY
Data sources: Datacite
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Landscape of Commercial Tools for Targets to Therapies

Authors: McLoughlin, Grant; Polinski, Nicole;

Landscape of Commercial Tools for Targets to Therapies

Abstract

This excel document presents a cursory landscape analysis of the commercially available tools available for the targets within the MJFF Targets to Therapies Initiative. One set includes TMEM175, TRPML1, ATP13A2, NOD2, OGA which were pursued in 2025. The second set includes STING1, TLR2, and TREM2 under evaluation in 2026. The third set includes GPNMB, VPS35, CTSB, BECN1, GALC, and GBAP1 under evaluation in 2026. ChatGPT assisted initial searches with manual refinement and curation. Monoclonal antibody landscape analysis was performed through searches of the online catalogs of Abcam, Thermofischer, Millipore Sigma, and Cell Signaling Technologies. Additional searches through CiteAb were performed when a large number of monoclonal antibodies were not available through the aforementioned vendors. Mouse model landscape analysis was performed through searchers of the International Mouse Strain Resource (IMSR) at findmice.org. Cell line landscape analysis was performed through searchers of the online catalogs of Abcam, Horizon Discovery, The Jackson Laboratory, and C-BIG repository (https://cbigr-open.loris.ca/ipsc_catalogue/). Viral vectors were identified intially through Google searches and searchers of the Vector Biolabs site. Assays were identified through searchers of online catalogs at Abcam and CiteAb. Compounds were identied through Google searchers and searchers in MedChemExpress. ChatGPT was used to enable searches, with information confirmed and expanded. Please note, additional reagents may be available for the tools that were missed by our search strategy. In addition, we do not have insight into the performance of these tools and therefore are not ranking them in any way or commenting on their quality. 

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citations
The total number of citations received by all articles of the researcher of interest.
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average