First master release with pre-built Apptainer SIF support and parameter estimation migration. Pre-built Apptainer SIF for SLURM containers Container image properties renamed from *_docker_name to *_apptainer_image with ORAS URL values SlurmProxy derives local SIF filenames from ORAS URLs; fail-fast on missing SIF CI build-and-publish-sif job publishes vcell-opt + vcell-batch SIFs to GHCR via ORAS See docs/apptainer-image-build.md for operational reference Parameter estimation migration (parest-bug branch) Database-backed job tracking (vc_optjob table) REST endpoints: POST/GET /api/v1/optimization Cross-protocol Artemis messaging (AMQP 1.0 ↔ OpenWire JMS) Desktop client rewritten to use generated OptimizationResourceApi Legacy /api/v0/optimization endpoints and socket server removed COPASI upgraded (basico 0.40→0.86, python-copasi 4.37→4.46) Other fixes Fix CodeQL partial path traversal alert #226 Restore executable permission on langevin_x64 in batch container Fail fast when notarytool submit fails Increase optimization polling timeout to 10 minutes Companion changes required vcell-fluxcd: rename properties in submit.env, add htc_singularity_imagedir, add vcell-sif-prepull k8s Job One-time: bootstrap vcell-solvers + vcell-fvsolver SIFs to GHCR via ORAS UI improvements (PR #1666) New renderers, extra options, dimming on mouse over, crosshair snap node highlight