The inter-linkages between environmental contamination, animal health, and food safety have emerged as critical concerns in the context of rapid industrialization and agricultural intensification. This study develops a policy integration model grounded in the One Health framework, using empirical evidence from Haryana, India. Heavy metals and pesticide residues originating from industrial and agricultural activities were traced across soil, water, livestock feed, and milk, demonstrating systemic transfer through the food chain. Health risk assessment indices, including Estimated Daily Intake (EDI), Hazard Quotient (HQ), and Cancer Risk (CR), indicate potential human health implications. The findings highlight the inadequacy of fragmented governance systems and propose an integrated, multi-sectoral policy model aligned with global sustainability goals. This research contributes to bridging the gap between environmental science and policy design, offering actionable insights for developing economies.