Abstract This work presents an extended comparative analysis of two modern parameter‑free models of fundamental physics: Topology of Totality (TOT), based on an information‑topological substrate of causal graphs, and the Law of the Unity of Being of the Triune Substance (ZEBTS), an ontologically‑structural theory deriving physical phenomena from the flytron dynamics of the Substance. TOT formulates physical reality as a structure on the Light Canvas, where the key parameter is the Sheaf Compressibility Index (SCI), which determines the degree of informational density of the causal graph. Spacetime, particle masses, quantum indeterminacy, and cosmological effects are derived from the spectral properties of graphs and the SCI‑deformed Heisenberg algebra. ZEBTS, in contrast, is built upon the ontological monism of the Triune Substance, where flytron operators generate spacetime, matter, quantum phenomena, and cosmological evolution as manifestations of semantic density and structural coherence. The article provides a systematic comparison of the ontological foundations, mathematical frameworks, physical consequences, cosmological predictions, mass‑generation mechanisms, interpretations of time, and metaphysical premises of both theories. It is shown that TOT can be interpreted as a special case of the low‑semantic‑density phase of ZEBTS, where graph structures represent projections of flytron configurations under semantic‑density reduction. Areas of agreement and contradiction are discussed, and an integration scheme is proposed in which ZEBTS serves as the ontological foundation, while TOT functions as a mathematical phenomenology describing the manifestations of the Substance in discrete informational structures.