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Feng-Lab-MIT/shank3_macaque_phenotyping: v1.0.0 - Macaque Phenotyping Pipeline

Authors: River;

Feng-Lab-MIT/shank3_macaque_phenotyping: v1.0.0 - Macaque Phenotyping Pipeline

Abstract

v1.0.0 — Initial Release This is the first public release of the analysis code accompanying the Shank3 macaque phenotyping manuscript. What's included Home Cage Behavioral Analysis (home_cage_scripts/) Pipeline for automated detection of stereotypic behaviors from DLC-tracked home cage recordings, including self-biting, repetitive/big motion, and pacing. Includes example data to run out of the box. Novel Environment Analysis (novel_environment_scripts/) Scripts for computing 3D travel distance in 5-minute bins and generating 3D head-position heatmaps from novel environment sessions, in real-world cage coordinates. Social Interaction Model (social_model_scripts/) Attention-based LSTM pipeline for unsupervised behavioral analysis of social interactions, covering model training, latent space extraction, PCA, and t-SNE clustering. EEG Recording Program (eeg_recording_program/) MATLAB scripts for MMN (mismatch negativity) EEG paradigm. Requirements Python 3.11, numpy < 2, TensorFlow 2.15 See requirements.txt in each subfolder for per-pipeline dependencies

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