TP53-mutant AML with ribosomal gene loss exhibits impaired protein translation and sensitivity to HSP90 inhibition
Spinella, Jean-François;
TP53-mutant AML with ribosomal gene loss exhibits impaired protein translation and sensitivity to HSP90 inhibition
This repository contains the scripts used to generate the figures and analyses in the manuscript. The code includes:- Copy-number analysis- Differential expression - Ribosomal eigengene computation - Mutation and cytogenetic association analyses- GSEA analysis Each script is annotated and uses generic input formats.