Background: Acne vulgaris is a common dermatological condition that can cause pain, itching, and psychosocial distress. Conventional medical treatments often provide limited relief in resistant cases. Case presentation: We present the case of a 21-year-old female with severe facial acne, associated pain, itching, redness, and dryness, unresponsive to multiple dermatological consultations. Yoga Prana Vidya (YPV) healing was initiated using psychotherapy, blood cleansing, and facial healing protocols, with additional localized healing for the affected area. The patient received 18 sessions over nine days, Results: Within three sessions, pain and itching reduced by 20%. By the end of the intervention, acne lesions reduced by 90%, with resolution of pain and itching. Follow-up confirmed complete recovery, sustained with Arhat Yoga practice, rhythmic breathing, and forgiveness sadhana. Conclusion: This case highlights the potential role of YPV healing as a complementary therapy in dermatology, supporting both physical and psychological recovery. Controlled studies are recommended to validate these findings.