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ZENODO
Article . 2026
License: CC BY
Data sources: ZENODO
ZENODO
Article . 2026
License: CC BY
Data sources: Datacite
ZENODO
Article . 2026
License: CC BY
Data sources: Datacite
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Evaluation of Equipotent Dose of Ropivacaine Heavy 0.75% V/S Bupivacaine 0.5% For Subarachnoid Block in Lower Limb and Lower Abdominal Surgeries

Authors: Dr Harshwardhan Tikle , Dr Megha Harshwardhan Tikle , Dr Avinash Nandawar , Dr Kadali Lakshmi Sudha;

Evaluation of Equipotent Dose of Ropivacaine Heavy 0.75% V/S Bupivacaine 0.5% For Subarachnoid Block in Lower Limb and Lower Abdominal Surgeries

Abstract

Background: Spinal anesthesia is widely used for lower limb and lower abdominal surgeries due to its rapid onset, reliable sensory and motor blockade, and minimal systemic drug exposure. Bupivacaine 0.5% heavy is commonly used for subarachnoid block; however, it is associated with prolonged motor blockade and potential cardiovascular toxicity. Ropivacaine, a newer long-acting amide local anesthetic, has been suggested as a safer alternative with less motor blockade and improved hemodynamic stability. This study was conducted to compare the characteristics of spinal anesthesia produced by equipotent doses of ropivacaine heavy 0.75% and bupivacaine heavy 0.5%. Aim: To compare the characteristics of central neuraxial blockade produced by ropivacaine heavy 0.75% and bupivacaine heavy 0.5% for subarachnoid block in lower limb and lower abdominal surgeries. Materials and Methods: A prospective, randomized, double-blinded comparative study was conducted on 60 patients belonging to ASA grade I and II, aged 18–75 years, undergoing lower limb and lower abdominal surgeries. Patients were randomly divided into two groups: Group I (n=30) received intrathecal ropivacaine heavy 0.75%, and Group II (n=30) received intrathecal bupivacaine heavy 0.5%. Parameters assessed included onset and duration of sensory and motor block, maximum sensory level achieved, time for two-segment regression, hemodynamic changes, and adverse effects. Results: Both groups had comparable demographic characteristics and similar onset of sensory block. However, the duration of sensory block, time for two-segment regression, and duration of motor blockade were significantly longer in the bupivacaine group (p <0.001). Hemodynamic parameters and oxygen saturation remained stable and comparable in both groups. Conclusion: Intrathecal ropivacaine heavy 0.75% provides effective spinal anesthesia with shorter motor blockade and comparable hemodynamic stability compared with bupivacaine heavy 0.5%, making it a useful alternative for lower limb and lower abdominal surgeries.

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average