Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ ZENODOarrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Article
Data sources: ZENODO
addClaim

Evaluation of Equipotent Dose of Ropivacaine Heavy 0.75% V/S Bupivacaine 0.5% For Subarachnoid Block in Lower Limb and Lower Abdominal Surgeries

Authors: Dr Harshwardhan Tikle , Dr Megha Harshwardhan Tikle , Dr Avinash Nandawar , Dr Kadali Lakshmi Sudha;

Evaluation of Equipotent Dose of Ropivacaine Heavy 0.75% V/S Bupivacaine 0.5% For Subarachnoid Block in Lower Limb and Lower Abdominal Surgeries

Abstract

Background: Spinal anesthesia is widely used for lower limb and lower abdominal surgeries due to its rapid onset, reliable sensory and motor blockade, and minimal systemic drug exposure. Bupivacaine 0.5% heavy is commonly used for subarachnoid block; however, it is associated with prolonged motor blockade and potential cardiovascular toxicity. Ropivacaine, a newer long-acting amide local anesthetic, has been suggested as a safer alternative with less motor blockade and improved hemodynamic stability. This study was conducted to compare the characteristics of spinal anesthesia produced by equipotent doses of ropivacaine heavy 0.75% and bupivacaine heavy 0.5%. Aim: To compare the characteristics of central neuraxial blockade produced by ropivacaine heavy 0.75% and bupivacaine heavy 0.5% for subarachnoid block in lower limb and lower abdominal surgeries. Materials and Methods: A prospective, randomized, double-blinded comparative study was conducted on 60 patients belonging to ASA grade I and II, aged 18–75 years, undergoing lower limb and lower abdominal surgeries. Patients were randomly divided into two groups: Group I (n=30) received intrathecal ropivacaine heavy 0.75%, and Group II (n=30) received intrathecal bupivacaine heavy 0.5%. Parameters assessed included onset and duration of sensory and motor block, maximum sensory level achieved, time for two-segment regression, hemodynamic changes, and adverse effects. Results: Both groups had comparable demographic characteristics and similar onset of sensory block. However, the duration of sensory block, time for two-segment regression, and duration of motor blockade were significantly longer in the bupivacaine group (p <0.001). Hemodynamic parameters and oxygen saturation remained stable and comparable in both groups. Conclusion: Intrathecal ropivacaine heavy 0.75% provides effective spinal anesthesia with shorter motor blockade and comparable hemodynamic stability compared with bupivacaine heavy 0.5%, making it a useful alternative for lower limb and lower abdominal surgeries.

Powered by OpenAIRE graph
Found an issue? Give us feedback