Granthi is described in Ayurveda as a localized nodular swelling formed due to the vitiation of Doshas along with the involvement of Rakta, Mamsa, and Meda Dhatu. Such nodular swellings may clinically resemble several benign proliferative conditions such as lipomas, cysts, lymphadenopathy, and thyroid nodules. Classical Ayurvedic literature elaborates the pathogenesis of Granthi through the concept of Dosha-Dhatu Sammurchana and Srotorodha leading to localized tissue proliferation. Among various medicinal plants indicated for glandular swellings, Kanchanar (Bauhinia variegata) is widely utilized because of its Kapha-Medohara, Lekhana, and Shothahara properties. The present review aims to analyze the Ayurvedic concept of Granthi and highlight the therapeutic potential of Kanchanar based on classical references and available pharmacological evidence.