This report synthesises the findings of Reports #01–#06 of the Tourism Systems & Development Series into a single comparative institutional analysis framework: the Tourism Sustainability Systems Framework (TSSF). The framework explains why tourism sustainability implementation systems consistently fail to produce independently verified outcomes at scale despite increasing policy commitment, certification coverage, and investment activity. Drawing on six analytical layers — operational conditions, community readiness, coordination architecture, educational transmission systems, governance architecture, and economic implementation architecture — the report demonstrates that implementation failure is structurally produced across multiple interacting institutional layers rather than resulting from isolated programme weaknesses or insufficient actor commitment. From the combined comparative evidence base, the report identifies six minimum structural conditions consistently associated with durable sustainability implementation systems. It shows that no existing implementation architecture in the current dataset satisfies these conditions simultaneously and explains why this absence reflects structural characteristics of the sector rather than shortcomings of individual initiatives. The Tourism Sustainability Systems Framework is presented as a diagnostic analytical architecture derived inductively from comparative evidence across governance and economic implementation environments. It establishes the structural conditions associated with implementation performance while explicitly distinguishing structural diagnosis from implementation architecture design. This publication forms Report #07 of the Tourism Systems & Development Series and provides the synthesis framework integrating the series’ governance, education, community readiness, and economic architecture findings.